冠脉慢性完全闭塞病变闭塞支数对心肌功能及心室重构的影响

承德医学院学报 ›› 2020, Vol. 37 ›› Issue (1): 15-17.

冠脉慢性完全闭塞病变闭塞支数对心肌功能及心室重构的影响

魏恒争

郑州市第一人民医院,河南郑州 450000

收稿日期:2019-07-30 出版日期:2020-02-10 发布日期:2021-11-19

EFFECTS OF OCCLUSION COUNTS OF CHRONIC CORONARY TOTAL OCCLUSION LESIONS ON MYOCARDIAL FUNCTION AND VENTRICULAR REMODELING

WEI Heng-zheng

Zhengzhou First People's Hospital, Henan Zhengzhou 45000, China

Received:2019-07-30 Online:2020-02-10 Published:2021-11-19

摘要/Abstract

摘要： 目的探讨不同冠脉支数慢性完全闭塞病变（CTO）对心肌功能、心室重构的影响。方法选择我院收治的124例CTO患者为研究对象,根据其闭塞支数分为单支闭塞组（n=77）、双支闭塞组（n=25）和多支闭塞组（n=22）,对比三组心肌功能[心肌肌钙蛋白I（cTnI）、N-端脑钠肽前体（NT-proBNP）、肌酸激酶（CK）、肌酸激酶同工酶（CK-MB）]和心室重构指标[左室舒张末期内径（LVEDD）、左室收缩末期内径（LVESD）、左心射血分数（LVEF）]。结果 cTnI、NT-proBNP、CK和CK-MB水平：多支闭塞组>双支闭塞组>单支闭塞组（P<0.05）;LVEDD、LVESD：多支闭塞组>双支闭塞组>单支闭塞组（P<0.05）,LVEF：多支闭塞组<双支闭塞组<单支闭塞组（P<0.05）。结论 CTO患者心肌功能、心室重构与CTO闭塞支数具有关联性,闭塞支数越多,CTO患者心肌功能越差、心室重构越严重。

关键词: 冠脉慢性完全闭塞病变（CTO）, 闭塞支数, 心肌功能, 心室重构

Abstract: Objective: To explore the effects of chronic total occlusion lesions (CTO) with different coronary artery counts on myocardial function and ventricular remodeling. Methods: 124 CTO patients were divided into single occlusion group (n=77), double occlusion group (n=25) and multiple occlusion group (n=22) according to occlusion counts. The myocardial function indexes [cardiac troponin I (cTnI), N-terminal pro-brain natriuretic peptide (NT-proBNP), creatine kinase (CK), creatine kinase isoenzyme (CK-MB)] and ventricular remodeling indexes [left ventricular end-diastolic diameter (LVEDD), left ventricular end-systolic diameter (LVESD), left ventricular ejection fraction (LVEF)] of patients in 3 groups were compared. Results: The level of cTnI, NT-proBNP, CK, CK-MB, LVEDD and LVESD showed that multiple occlusion group>double occlusion group>single occlusion group (P<0.05). The LVEF showed that multiple occlusion group<double occlusion group<single occlusion group (P<0.05). Conclusions: The myocardial function and ventricular remodeling in CTO patients are associated with CTO occlusion counts. The more occlusion counts, the worse myocardial function and the more serious ventricular remodeling in CTO patients.

Key words: Chronic coronary total occlusion lesions (CTO), Occlusion counts, Myocardial function, Ventricular remodeling

中图分类号:

R543.3

魏恒争. 冠脉慢性完全闭塞病变闭塞支数对心肌功能及心室重构的影响[J]. 承德医学院学报, 2020, 37(1): 15-17.

WEI Heng-zheng. EFFECTS OF OCCLUSION COUNTS OF CHRONIC CORONARY TOTAL OCCLUSION LESIONS ON MYOCARDIAL FUNCTION AND VENTRICULAR REMODELING[J]. Journal of Chengde Medical University, 2020, 37(1): 15-17.

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