降钙素原和白介素6在急性胆囊炎合并细菌感染中的诊断价值

承德医学院学报 ›› 2019, Vol. 36 ›› Issue (1): 21-23.

降钙素原和白介素6在急性胆囊炎合并细菌感染中的诊断价值

陈国利, 郑志方, 张学军^△

承德医学院附属医院,河北承德 067000

收稿日期:2018-10-18 出版日期:2019-02-10 发布日期:2021-11-18
通讯作者: △

DIAGNOSTIC VALUE OF PROCALCITONIN AND INTERLEUKIN6 IN ACUTE CHOLECYSTITIS COMBINED WITH BACTERIAL INFECTION

CHEN Guo-li, ZHENG Zhi-fang, ZHANG Xue-jun

the Affiliated Hospital of Chengde Medical College, Hebei Chengde 067000, China

Received:2018-10-18 Online:2019-02-10 Published:2021-11-18

摘要/Abstract

摘要： 目的:探讨检测降钙素原(PCT)和白介素6（IL-6）在急性胆囊炎合并细菌感染中的诊断价值。方法:82例急性胆囊炎患者根据是否存在细菌感染分为细菌感染组25例和非细菌感染组57例,分别检测两组患者PCT和IL-6水平,并建立ROC曲线评估二者对急性胆囊炎合并细菌感染的诊断价值。结果:细菌感染组急性胆囊炎患者PCT、IL-6水平均明显高于非细菌感染组,组间比较差异具有统计学意义（P<0.05）。PCT的ROC曲线下面积（AUC）为0.904,95%置信区间为0.819~0.989;IL-6的ROC曲线下面积（AUC）为0.855,95%置信区间为0.738~0.972。结论:急性胆囊炎合并细菌感染时PCT和IL-6的水平均明显升高,二者对判断急性胆囊炎合并细菌感染均有较高的诊断价值。

关键词: 急性胆囊炎, 细菌感染, 降钙素原, 白介素6

Abstract: Objective: To investigate the diagnostic value of procalcitonin (PCT) and interleukin 6 (IL-6) in acute cholecystitis combined with bacterial infection. Methods: 82 acute cholecystitis patients were divided into bacterial infection group (n=25) and non bacterial infection group (n=57) according to whether had bacterial infection. The blood PCT and IL-6 level of all the patients were detected and ROC curve was established to evaluate the diagnostic value of PCT and IL-6 in acute cholecystitis combined with bacterial infection. Results: The PCT and IL-6 level of acute cholecystitis patients in bacterial infection group were obviously higher than non bacterial infection group (P<0.05). The AUC of PCT was 0.904, 95% confidence interval was 0.819~0.989; the AUC of IL-6 was 0.855, 95% confidence interval was 0.738~0.972. Conclusions: The PCT and IL-6 level of acute cholecystitis combined with bacterial infection patients significantly increase, and both of them have high diagnostic value in judging acute cholecystitis combined with bacterial infection.

Key words: Acute cholecystitis, Bacterial infection, Procalcitonin, Interleukin 6

中图分类号:

R575.6

陈国利, 郑志方, 张学军. 降钙素原和白介素6在急性胆囊炎合并细菌感染中的诊断价值[J]. 承德医学院学报, 2019, 36(1): 21-23.

CHEN Guo-li, ZHENG Zhi-fang, ZHANG Xue-jun. DIAGNOSTIC VALUE OF PROCALCITONIN AND INTERLEUKIN6 IN ACUTE CHOLECYSTITIS COMBINED WITH BACTERIAL INFECTION[J]. Journal of Chengde Medical University, 2019, 36(1): 21-23.

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