正常体重指数围绝经期女性腹型肥胖与围绝经期综合征关系的研究

承德医学院学报 ›› 2023, Vol. 40 ›› Issue (5): 381-384.

正常体重指数围绝经期女性腹型肥胖与围绝经期综合征关系的研究

陶静¹, 赵桂君², 严晔华¹, 崔丽梅¹, 鞠蕊^3,*

1. 北京市垂杨柳医院内分泌科,北京 100022;
2. 北京市垂杨柳医院妇产科;
3. 首都医科大学附属北京妇产医院/北京妇幼保健院

收稿日期:2022-12-22 出版日期:2023-10-10 发布日期:2023-12-18
通讯作者: *
基金资助:
北京市朝阳区科技计划项目（CYSF1713）

The Study on the Relationship between Abdominal Obesity and Climacteric Syndromes in Perimenopausal Women with Normal Body Weight

TAO Jing¹, ZHAO Gui-jun², YAN Ye-hua¹, CUI Li-mei¹, JU Rui^3,*

1. Departmemt of Endocrinology, Beijing ChuiYangLiu Hospital, Beijing, 100022, China;
2. Departmemt of Obstetrics and Gynecology, Beijing ChuiYangLiu Hospital;
3. Beijing Obstetrics and Gynecology Hospital, Capital Medical University. Beijing Maternal and Child Health Care

Received:2022-12-22 Online:2023-10-10 Published:2023-12-18

摘要/Abstract

摘要： 目的调查正常体重指数（BMI）围绝经期女性的围绝经期综合征状况,分析腹型肥胖对围绝经期女性更年期综合征的影响。方法根据“生殖衰老研讨会分期+10”,纳入2018年6月~2019年6月在北京市垂杨柳医院妇科以及内分泌科就诊并且符合纳入、排除标准的335例围绝经期女性为研究对象。根据腰臀比（WHR）分为正常组（A组）和腹型肥胖组（B组）。采用改良Kupperman评分表（KMI）评估围绝经期症状,比较KMI总分及各维度评分在2组间的差异,通过Pearson相关性分析评估WHR与KMI评分以及各维度评分间的关系。结果在2组不同WHR的围绝经期女性中,B组围绝经期女性的KMI总分以及潮热出汗、感觉障碍、失眠3个维度的评分比较差异有统计学意义（P<0.05）;WHR与KMI评分以及潮热出汗、感觉障碍、失眠3个维度呈正相关关系（P<0.05）。结论正常BMI的围绝经期女性腹型肥胖与围绝经期综合征的严重程度呈正相关关系,临床医生在日常工作中有必要对此时期的女性进行体重管理教育和有针对性的健康指导。

关键词: 体重指数, 肥胖, 腹型肥胖, 围绝经期综合征, 女性健康

Abstract: Objective The purpose of this research is to analyze the presence of climacteric syndromes in perimenopausal women with normal body weight and varying waist hip ratios (WHR). Furthermore, the investigation will explore the connection between abdominal obesity and climacteric syndromes in this group. Methods According to the 2011 stages of the Reproductive Ageing Workshop (STRAW+10), this study was conducted among 335 perimenopausal women who met the inclusion and exclusion criteria and admitted to the departmem of Endocrinology and the Department of Gynecology, Beijing ChuiYangLiu Hospital from June 2018 to June 2019. According to WHR, these women were divided into normal group (group A) and abdominal obesity group (group B). The modified Kupperman Index was used to evaluate climacteric syndromes, an examination of the total score and scores of each dimension of KMI between the two groups was conducted.. The correlation between WHR and the KMI scores, as well as each dimension score, was evaluated by Pearson correlation analysis. Results The scores of KMI, hot flashes, sensory disturbance, insomnia in group B were significantly higher than those in group A (P<0.05). WHR was positively correlated with the scores of KMI hot flashes, sensory disturbance and insomnia (P<0.05). Conclusion This study reveals that abdominal obesity in perimenopausal women were positively correlated with the severity of climacteric syndrome. It is imperative that clinicians give weight management education and tailored health guidance to women in their daily practice.

Key words: trastuzumab, SOX scheme, human epidermal growth factor receptor 2, advanced gastric cancer, tumor marker, immune function

中图分类号:

R711

陶静, 赵桂君, 严晔华, 崔丽梅, 鞠蕊. 正常体重指数围绝经期女性腹型肥胖与围绝经期综合征关系的研究[J]. 承德医学院学报, 2023, 40(5): 381-384.

TAO Jing, ZHAO Gui-jun, YAN Ye-hua, CUI Li-mei, JU Rui. The Study on the Relationship between Abdominal Obesity and Climacteric Syndromes in Perimenopausal Women with Normal Body Weight[J]. Journal of Chengde Medical University, 2023, 40(5): 381-384.

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