胰岛β细胞功能障碍与2型糖尿病相关研究进展

摘要/Abstract

中图分类号:

韩思雨, 易梦雅, 李警耀, 张睿, 陈志宏. 胰岛β细胞功能障碍与2型糖尿病相关研究进展[J]. 承德医学院学报, 2025, 42(3): 230-234.

导出引用管理器 EndNote|Ris|BibTeX

链接本文: http://tougao.cdmc.edu.cn:8088/CN/

http://tougao.cdmc.edu.cn:8088/CN/Y2025/V42/I3/230

[1] Saeedi P, Petersohn I, Salpea P, et al.Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9th edition[J]. Diabetes Res Clin Pr, 2019, 157: 107843.
[2] Zheng Y, Ley SH, Hu FB.Global aetiology and epidemiology of type 2 diabetes mellitus and its complications[J]. Nat Rev Endocrinology, 2018, 14(2): 88-98.
[3] Inaishi J, Saisho Y.Beta-Cell Mass in Obesity and Type 2 Diabetes, and Its Relation to Pancreas Fat: A Mini-Review[J]. Nutrients, 2020, 12(12): 3846.
[4] Hannon TS, Kahn SE, Utzschneider KM, et al.Review of methods for measuring β-cell function: Design considerations from the Restoring Insulin Secretion (RISE) Consortium[J]. Diabetes Obes Metab, 2018, 20(1): 14-24.
[5] Bunney PE, Zink AN, Holm AA, et al.Orexin activation counteracts decreases in nonexercise activity thermogenesis (NEAT) caused by high-fat diet[J]. Physiology &Behavior, 2017, 176: 139-148.
[6] Guest PC.Biogenesis of the Insulin Secretory Granule in Health and Disease[J]. Adv Exp Med Biol, 2019, 1134: 17-32.
[7] Galal MA, Alouch SS, Alsultan BS, et al.Insulin Receptor Isoforms and Insulin Growth Factor-like Receptors: Implications in Cell Signaling, Carcinogenesis, and Chemoresistance[J]. Int J Mol Sci, 2023, 24(19): 15006.
[8] Lin J, Song T, Li C, et al.GSK-3β in DNA repair, apoptosis, and resistance of chemotherapy, radiotherapy of cancer[J]. Biochim Biophys Acta Mol Cell Res, 2020, 1867(5): 118659.
[9] Papazafiropoulou AK, Papanas N, Melidonis A, et al.Family History of Type 2 Diabetes: Does Having a Diabetic Parent Increase the Risk?[J]. Current Diabetes Reviews, 2017, 13(1): 19-25.
[10] Kral BG, Becker DM, Yanek LR, et al.The relationship of family history and risk of type 2 diabetes differs by ancestry[J]. Diabetes Metabolism, 2019, 45(3): 261-267.
[11] Al-Sulaiti H, Diboun I, Agha MV, et al.Metabolic signature of obesity-associated insulin resistance and type 2 diabetes[J]. J Transl Med, 2019, 17(1): 348.
[12] Fang X, Miao R, Wei J, et al.Advances in multi-omics study of biomarkers of glycolipid metabolism disorder[J]. Comput Struct Biotechnol J,2022, 20: 5935-5951.
[13] Marciniak SJ, Chambers JE, Ron D.Pharmacological targeting of endoplasmic reticulum stress in disease[J]. Nature Reviews Drug Discovery, 2022, 21(2): 115-140.
[14] Yaribeygi H, Sathyapalan T, Atkin SL, et al.Molecular Mechanisms Linking Oxidative Stress and Diabetes Mellitus[J]. Oxidative Medicine and Cellular Longevity, 2020, 2020: 8609213.
[15] Ezraty B, Gennaris A, Barras F, et al.Oxidative stress, protein damage and repair in bacteria[J]. Nature Reviews Microbiology, 2017, 15(7): 385-396.
[16] Singh A, Kukreti R, Saso L, et al.Mechanistic Insight into Oxidative Stress-Triggered Signaling Pathways and Type 2 Diabetes[J]. Molecules, 2022, 27(3): 950.
[17] Fang FS, Cheng XL, Gong YP, et al.Association between glycemic indices and beta cell function in patients with newly diagnosed type 2 diabetes[J]. Current Medical Research and Opinion, 2014, 30(8): 1437-1440.
[18] Shen Y, Prinyawiwatkul W, Xu Z.Insulin: a review of analytical methods[J]. The Analyst, 2019, 144(14): 4139-4148.
[19] Ahrén B, Pratley RE, Soubt M, et al.Clinical measures of islet function: usefulness to characterize defects in diabetes[J]. Current Diabetes Reviews, 2008, 4(2): 129-145.
[20] Zhao Y, Li H.Association of serum leptin and insulin levels among type 2 diabetes mellitus patients: A case-control study[J]. Medicine (Baltimore), 2022, 101(41): e31006.
[21] Beamish CA, Gaber AO, Fraga DW, et al.Pretransplant HOMA-β Is Predictive of Insulin Independence in 7 Patients With Chronic Pancreatitis Undergoing Islet Autotransplantation[J]. Transplant Direct, 2022, 8(10): e1367.
[22] Mather KJ, Tjaden AH, Hoehn A, et al.Precision and accuracy of hyperglycemic clamps in a multicenter study[J]. American Journal of Physiology Endocrinology and Metabolism, 2021, 320(4): E797-E807.
[23] Phillips PJ.Oral glucose tolerance testing[J]. Australian Family Physician, 2012, 41(6): 391-393.
[24] Morettini M, Di Nardo F, Burattini L, et al.Assessment of glucose effectiveness from short IVGTT in individuals with different degrees of glucose tolerance[J]. Acta Diabetologica, 2018, 55(10): 1011-1018.
[25] AL-Mrabeh A, Hollingsworth KG, Steven S, et al.Morphology of the pancreas in type 2 diabetes: effect of weight loss with or without normalisation of insulin secretory capacity[J]. Diabetologia, 2016, 59(8): 1753-1759.
[26] Wu YJ, Fang ZH, Zheng SG.Effects of danzhi jiangtang Capsule combined exercise on pancreatic oxidative stress and islet beta-cell function in diabetic rats[J]. Zhongguo Zhong Xi Yi Jie He Za Zhi, 2012, 32(11): 1531-1534.
[27] GRADE Study Research Group, Nathan DM, Lachin JM, et al. Glycemia Reduction in Type 2 Diabetes - Glycemic Outcomes[J]. The New England Journal of Medicine, 2022, 387(12): 1063-1074.
[28] 曾静,方毅. 糖尿病药物治疗的现状及药物研究进展[J]. 临床药物治疗杂志,2017,15(10):1-5.
[29] Razzaghy-Azar M, Nourbakhsh M, Talea A, et al.Meglitinide (repaglinide) therapy in permanent neonatal diabetes mellitus: two case reports[J]. Journal of Medical Case Reports, 2021, 15(1): 535.
[30] Chen X, Lv X, Yang G, et al.Polyethylene glycol loxenatide injections added to metformin effectively improve glycemic control and exhibit favorable safety in type 2 diabetic patients[J]. Journal of Diabetes, 2017, 9(2): 158-167.
[31] Lebovitz HE.Thiazolidinediones: the Forgotten Diabetes Medications[J]. Current Diabetes Reports, 2019, 19(12): 151.
[32] Niswender KD.Basal insulin: physiology, pharmacology, and clinical implications[J]. Postgraduate Medicine, 2011, 123(4): 17-26.
[33] 王勇,王存川,朱晒红,等. 中国肥胖及2型糖尿病外科治疗指南(2019版)[J]. 中国实用外科杂志,2019,39(4):301-306.
[34] Zhang Y, Zhu C, Wen X, et al.Laparoscopic sleeve gastrectomy improves body composition and alleviates insulin resistance in obesity related acanthosis nigricans[J]. Lipids in Health and Disease, 2017, 16(1): 209.
[35] Jørgensen NB, Jacobsen SH, Dirksen C, et al.Acute and long-term effects of Roux-en-Y gastric bypass on glucose metabolism in subjects with Type 2 diabetes and normal glucose tolerance[J]. Am J Physiol Endocrinol Metab, 2012, 303(1): E122-131.
[36] Polyzogopoulou EV, Kalfarentzos F, Vagenakis AG, et al.Restoration of euglycemia and normal acute insulin response to glucose in obese subjects with type 2 diabetes following bariatric surgery[J]. Diabetes, 2003, 52(5): 1098-1103.

胰岛β细胞功能障碍与2型糖尿病相关研究进展

PDF

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

编辑推荐

Metrics

本文评价

[1]	韩思雨, 李雨欣, 易梦雅, 李警耀, 陈志宏. 丝胶靶向Akt1调控PI3K/Akt信号通路促进STZ致损伤INS-1细胞增殖[J]. 承德医学院学报, 2024, 41(2): 96-100.
[2]	李娟, 徐家新, 王春, 王艳秋, 周路路. 血清Betatrophin对2型糖尿病合并代谢相关脂肪性肝病预测价值的研究[J]. 承德医学院学报, 2023, 40(6): 467-471.
[3]	生庆海, 刘成, 贾艳菊, 刘晶, 谢颖, 李增宁, 田婷婷. “觉甘”食品对T2DM患者餐后IFG改变的研究[J]. 承德医学院学报, 2023, 40(2): 172-175.
[4]	贾彦彦, 薛培举. SGLT2抑制剂治疗2型糖尿病合并心力衰竭及对ST2、NT-proBNP水平的影响[J]. 承德医学院学报, 2023, 40(1): 28-31.
[5]	王梅, 姜超, 裴存文. 女性T2DM患者并发DR新型危险因素筛选及诊断预测模型构建[J]. 承德医学院学报, 2022, 39(5): 385-388.
[6]	胡万祥, 李金尧, 李雨欣, 韩思雨, 程露阳, 陈志宏. 丝胶通过影响自噬和氧化应激发挥保护STZ致胰岛素瘤细胞损伤的作用[J]. 承德医学院学报, 2022, 39(3): 186-192.
[7]	阮鸿娇, 葛婷, 胡万祥, 李金尧, 宋成军, 陈志宏. 线粒体动力学、炎症与2型糖尿病[J]. 承德医学院学报, 2021, 38(3): 234-238.
[8]	伍文耀, 何清香, 陈秋芳, 李德海. 2型糖尿病患者馒头餐前后血清人神经肽水平的变化[J]. 承德医学院学报, 2021, 38(1): 16-19.
[9]	林坚, 朱忠华, 宋湘穗. T2DM并发代谢性炎症综合征危险因素分析[J]. 承德医学院学报, 2020, 37(4): 294-295.
[10]	王楠, 朱红涛, 刘晓燕. 网膜素-1、内脂素、谷氨酰转肽酶与2型糖尿病患者CIMT的相关性[J]. 承德医学院学报, 2020, 37(3): 198-200.
[11]	张银广, 王佳宇, 李朴涵, 吴合亮, 王鹏, 刘东慧. 2型糖尿病大鼠肝脏IRS-1的变化及丝胶的调节作用^*[J]. 承德医学院学报, 2020, 37(2): 101-104.
[12]	王胜强. 肥胖型男性2型糖尿病患者性激素和骨钙素水平的变化及其与IR的相关性[J]. 承德医学院学报, 2020, 37(1): 25-27.
[13]	付丹丹. 结构式团体心理干预对2型糖尿病患者心理状态和治疗依从性的影响[J]. 承德医学院学报, 2019, 36(6): 502-504.
[14]	刘雨轩, 刘晓燕, 高宇, 孙志新. 骨转换标记物与2型糖尿病微血管并发症的关系[J]. 承德医学院学报, 2019, 36(3): 198-201.
[15]	刘东慧, 刘陈霏, 宋妤轩, 阮鸿娇, 陈志宏. 丝胶对2型糖尿病大鼠胰腺Akt的调节作用^*[J]. 承德医学院学报, 2019, 36(3): 254-256.