关键词: 妊娠期糖尿病（GDM）, 钠钾镁钙葡萄糖注射液, 剖宫产

Abstract: Objective: To observe the clinical application value of sodium, potassium, magnesium, calcium and glucose injection for pregnant women with gestational diabetes (GDM) before cesarean section. Methods: 60 GDM parturients were randomly divided into two groups: sodium, potassium, magnesium, calcium and glucose injection group (experimental group) and lactate Ringer's solution group (control group) with 30 parturients in each group. Preloading was carried out according to 10ml/kg after parturients entering operating room. The mean arterial pressure (MAP) and heart rate of parturients in 2 groups at immediately after entering the operating room (T0), the end of preloading before anaesthesia (T1), 5min after anesthesia (T2), immediately after cord cut (T3) and end of operation (T4) were recorded respectivly. The blood glucose and lactate level of parturients were measured by extracting maternal arterial blood at T0, T3, T4. The occurrence of hypotension, nausea and vomiting, as well as using of vasoactive drugs during operation were also recorded. Results: There was no significant difference in heart rate and MAP between the experimental group and control group at each timing (P>0.05). There was no significant difference in incidence rate of hypotension, nausea and vomiting, as well as utilization rate of vasoactive drugs between the two groups (P>0.05). The blood glucose of parturients in experimental group at T3, T4 were obviously higher than control group, but the lactate levels were obviously lower (P<0.05). Conclusions: Using of sodium, potassium, magnesium, calcium and glucose injection for GDM parturients before cesarean section is beneficial to maintain the circulation stability during operation; it also can improve the blood glucose within the safe range, but does not cause increasing of lactate level.

Key words: Gestational diabetes (GDM), Sodium, potassium, magnesium, calcium and glucose injection, Cesarean section