生物羊膜镜和角膜绷带镜对翼状胬肉患者角膜影响研究

摘要/Abstract

摘要： 目的探究自体游离结膜瓣移植术治疗翼状胬肉时,使用生物羊膜镜及角膜绷带镜治疗的疗效差异。方法我院2017年6月~2019年10月收治161例（169眼）翼状胬肉患者,患者均接受自体游离结膜瓣移植术治疗,将术中应用生物羊膜镜、角膜绷带镜及不应用任何辅助材料治疗患者分别纳入羊膜镜组（n=51例,54眼）和角膜绷带镜组（n=54例,55眼）及对照组（n=56,60眼）。比较三组患者手术前后最佳矫正视力、角膜情况、治疗效果。结果三组患者手术后3个月最佳矫正视力较手术前显著上升,角膜地形图表面不对称指数、角膜散光度及表面规则指数较手术前显著下降（P<0.05）;术后3个月,角膜绷带镜组与羊膜镜组患者最佳矫正视力高于对照组,角膜地形图表面不对称指数、角膜散光度及表面规则指数低于对照组;角膜绷带镜组患者最佳矫正视力显著高于羊膜镜组,角膜地形图表面不对称指数、角膜散光度及表面规则指数显著低于羊膜镜组（P<0.05）。绷带镜组、羊膜镜组及对照组患者手术治疗效果比较,差异具有统计学意义（P<0.05）;绷带镜组、羊膜镜组患者复发率显著低于对照组（P<0.05）,绷带镜组、羊膜镜组患者复发率比较,差异无统计学意义（P>0.05）。结论翼状胬肉患者自体游离结膜瓣移植术中,应用角膜绷带镜及生物羊膜镜治疗效果优于单纯翼状胬肉患者自体游离结膜瓣移植术,可以促进患者角膜创面快速康复,减轻患者手术后角膜散光程度,其中角膜绷带镜治疗效果最佳。

关键词: 生物羊膜镜, 角膜绷带镜, 翼状胬肉

Abstract: Objective To explore the differences in curative effect between biological amnioscope and corneal bandage lens in autologous free conjunctival flap transplantation for pterygium. Methods The related data of 161 patients (169 affected eyes) with pterygium who were admitted to the hospital from June 2017 to October 2019 were collected. All patients were treated with autologous free conjunctival flap transplantation. Patients treated with biological amnioscope, corneal bandage lens and those not treated with any auxiliary materials were included in amnioscope group (n=51, 54 affected eyes), corneal bandage lens group (n=54, 55 affected eyes) and the control group (n=56, 60 affected eyes). The best corrected visual acuity (BCVA), corneal condition before and after surgery and the therapeutic effect were compared among the three groups. Results BCVA of all groups significantly increased three months after surgery, while the corneal topographic surface asymmetry index, corneal astigmatism and surface regularity index significantly decreased (P<0.05). Three months after surgery, the order of BCVA in the three groups from high to low was as follows: the corneal bandage lens group, the amnioscope group, the control group. The order of corneal topographic surface asymmetry index, corneal astigmatism and surface regularity index from low to high was as follows: the corneal bandage lens group, the amnioscope group, the control group (P<0.05). The differences in surgical effects among the three groups were statistically significant (P<0.05). The recurrence rates in the corneal bandage lens group and the amnioscope group were significantly lower than that of the control group (P<0.05), but there was no statistically significant between the corneal bandage lens group and the amnioscope group (P>0.05). Conclusion The curative effect of autologous free conjunctival flap transplantation with corneal bandage lens and biological amnioscope is better than that of simple autologous free conjunctival flap transplantation in the treatment of pterygium. The former can promote rapid recovery from corneal wounds, and reduce corneal astigmatism after surgery. Besides, the effect of corneal bandage lens is the best.

Key words: biological amnioscope, corneal bandage lens, pterygium

中图分类号:

R779.64

杨新爱. 生物羊膜镜和角膜绷带镜对翼状胬肉患者角膜影响研究[J]. 承德医学院学报, 2020, 37(4): 284-286.

YANG Xin-ai. Study on the Effect of Biological Amnioscope and Corneal Bandage Lens on Corneas of Patients with Pterygium[J]. Journal of Chengde Medical University, 2020, 37(4): 284-286.

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