Abstract: Objective: To probe the ureaplasma urealyticum infection (UU) in pregnancy and analyze the influences of UU infection on pregnancy outcome. Methods: The UU infection of 286 early and mid pregnant women in our hospital, as well as 150 non pregnant women of childbearing age were detected and the pregnancy outcome of all the pregnant women were tracked. The UU positive pregnant women were divided into antibiotics treatment group and non antibiotics treatment group according to the use of antibiotics; the UU infection were rechecked after treatment, and the UU cure rate and normal parturition rate were recorded. Results: The positive rate of UU infection in 286 pregnant women was 39.16% (112/286), which was obviously higher than non pregnant women of childbearing age (28.67%, P<0.05). The adverse pregnancy outcomes of UU infection group was 53.57% (60/112), which was obviously higher than UU negative group (26.44%, P<0.05). The UU cure rate and normal parturition rate of antibiotics treatment group were respectively 88.61% (70/79) and 62.02% (49/79), which were obviously higher than non antibiotics treatment group (12.12%, 9.09%, P<0.05). Conclusions: The UU infection rate of pregnant women is obviously higher than non pregnant women of childbearing, and UU infection is closely related to adverse pregnancy outcomes. Pregnant women with UU infection should be treated with sensitive antibiotics as soon as possible in order to reduce the impacts of UU infection on pregnancy outcome.

Key words: Pregnancy, Ureaplasma urealyticum (UU), Pregnancy outcome

摘要： 目的: 了解我院孕期解脲支原体（UU）感染现状,并分析UU感染对妊娠结局的影响。方法: 检测我院286名早、中期孕妇及150名育龄非妊娠妇女宫颈分泌物UU感染情况,跟踪孕妇的妊娠结局。对于UU阳性孕妇,根据是否使用抗生素分为抗生素治疗组和非抗生素治疗组,治疗后复查UU,记录UU治愈率和正常分娩率。结果: 286名孕妇UU感染阳性率为39.16%（112/286）,明显高于育龄非妊娠妇女（28.67%,P<0.05）。UU感染组出现不良妊娠结局60例,占53.57%,明显高于UU阴性组（26.44%,P<0.05）。抗生素治疗组孕妇UU治愈率、正常分娩率分别为88.61%（70/79）、62.02%（49/79）,均明显高于非抗生素治疗组（12.12%、9.09%,P<0.05）。结论: 与非妊娠育龄妇女相比,孕期UU感染率较高,而UU感染与妊娠预后不良密切相关;孕妇发生UU感染后应尽早合理选用敏感抗生素进行治疗,以降低UU感染对妊娠结局的影响。

关键词: 妊娠, 解脲支原体（UU）, 妊娠结局