Abstract: Objective: To study the relationships between common digestive diseases and Helicobactor pylori infection in Chengde area. Method: The gastric mucosa specimens of 1036 patients (urease test positive) with chronic gastritis, duodenal ulcer, gastric ulcer, complex ulcer, dyspepsia, gastric carcinoma in Chengde Central Hospital were taken for Helicobactor pylori culture. Results: Among 1036 patients, the Helicobactor pylori were positive in 448 patients and the positive rate was 43.2%. The Helicobactor pylori positive rate in different digestive system diseases in Chengde area from high to low was dyspepsia (100%), duodenal ulcer (69.3%), complex ulcer (68.3%), gastric ulcer (49.4%), gastric carcinoma (29.3%) and chronic gastritis (19.8%). Conclusions: In Chengde area, the common digestive diseases, such as chronic gastritis, dyspepsia, peptic ulcer and gastric cancer are closely related to Helicobactor pylori infection. Correct understanding and treatment ofHelicobacter pylori infection has positive significances for reducing disease burden and improving the life quality of patients.

Key words: Chengde area, Helicobactor pylori, Common digestive diseases

摘要： 目的: 研究承德地区常见消化系统疾病与幽门螺旋杆菌感染的关系。方法: 以就诊于承德市中心医院,尿素酶试验阳性的1036例慢性胃炎、十二指肠溃疡、胃溃疡、复合溃疡、消化不良、胃癌患者为研究对象,取胃黏膜标本进行幽门螺旋杆菌培养。结果: 1036例患者中,幽门螺旋杆菌阳性448例,阳性率为43.2%。承德地区不同消化系统疾病幽门螺旋杆菌培养阳性率依次为：消化不良100%、十二指肠溃疡69.3%、复合溃疡68.3%、胃溃疡49.4%、胃癌29.3%、慢性胃炎19.8%。结论: 承德地区慢性胃炎、消化不良、消化性溃疡、胃癌等常见消化系统疾病与幽门螺旋杆菌感染密切相关,正确认识及处理幽门螺旋杆菌感染,对于降低疾病负担、改善患者的生活质量有积极意义。

关键词: 承德地区, 幽门螺旋杆菌, 常见消化系统疾病