Abstract: Objective: To investigate the clinical effects of ureteroscopic holmium laser lithotripsy on treating upper urinary calculi patients. Methods: 42 upper urinary calculi patients treated with ureteroscopic holmium laser lithotripsy were selected as observation group; 42 patients treated with percutaneous nephrolithotomy were selected as control group at the same term. The operation time, intraoperative blood loss, postoperative gastrointestinal peristalsis time, stone clearance rate and postoperative complications of 2 groups were compared. Results: The operation time of observation group was obviously longer than control group (P<0.05); the intraoperative blood loss, postoperative gastrointestinal peristalsis time and incidence rate of complications of observation group were obviously lower than control group (P<0.05). There was no statistical significance in stone clearance rate between observation group and control group (P>0.05). Conclusions: Treating upper urinary calculi (<2cm) with ureteroscopic holmium laser lithotripsy has the advantages of high stone clearance rate and less postoperative complications, so it is a safe and effective method in the treatment of upper urinary calculi.

Key words: Ureteroscopic holmium laser lithotripsy, Upper urinary calculi, Renal calculi, Application effect

摘要： 目的: 探讨输尿管软镜钬激光碎石术治疗上尿路结石的临床效果。方法: 42例采用输尿管软镜钬激光碎石术治疗的上尿路结石患者为观察组,同期42例采用经皮肾镜碎石术治疗的上尿路结石患者作为对照组。比较两组患者手术时间、术中出血量、术后胃肠蠕动时间、结石清除率及术后并发症情况。结果: 观察组手术时间明显长于对照组,术中出血量、术后胃肠蠕动时间、并发症发生率明显低于对照组（P<0.05）;两组患者结石清除率比较,差异无统计学意义（P>0.05）。结论: 输尿管软镜钬激光碎石术治疗结石直径小于2cm的上尿路结石具有结石清除率高、术后并发症少的优点,是治疗上尿路结石安全有效的方法。

关键词: 输尿管软镜钬激光碎石术, 上尿路结石, 肾结石, 应用效果