Abstract: Objective:To analyze the diagnostic value of serum procalcitonin (PCT) detection in children with bacterial upper respiratory tract infection. Methods:The serum PCT and C reactive protein (CRP) level, white blood cell (WBC) and sputum culture of 108 children with suspected bacterial upper respiratory tract infection that were treated in Qingdao Eighth People's Hospital from 2015.7 to 2017.5 were detected. The diagnostic value of serum PCT level,CRP and WBC for children with bacterial upper respiratory tract infection were analyzed by taking the results of sputum culture as gold standard. Results:Among 108 children, the sputum culture showed 72 children with bacterial upper respiratory tract infection. The serum PCT, CRP level and WBC of children with bacterial upper respiratory tract infection were all obviously higher than non bacterial upper respiratory tract infection (P<0.05). Taking the results of sputum culture as gold standard, the sensitivity, specificity, positive predictive value, negative predictive value and accuracy rate of serum PCT in diagnosis of bacterial upper respiratory tract infection were higher than CRP and WBC (P<0.05). Conclusions:The serum PCT detection has higher diagnostic value for children with bacterial upper respiratory tract infection, and has higher diagnostic sensitivity and specificity than CRP and WBC.

Key words: Bacterial upper respiratory tract infection, Procalcitonin, Diagnosis

摘要： 目的: 分析血清降钙素原（PCT）对细菌性上呼吸道感染患儿的诊断价值。方法: 选取我院于2015年7月-2017年5月期间收入的疑似细菌性上呼吸道感染患儿108例,均进行血清PCT、C反应蛋白（CRP）、白细胞计数（WBC）检测以及痰培养,以痰培养结果为金标准,评估血清PCT、CRP、WBC对细菌性上呼吸道感染的诊断价值。结果: 痰培养结果显示,细菌性上呼吸道感染72例,非细菌性上呼吸道感染36例;细菌性上呼吸道感染患儿血清PCT、CRP、WBC水平均高于非细菌性上呼吸道感染患儿,差异具有统计学意义（P<0.05）;以痰培养诊断结果为金标准,血清PCT诊断细菌性上呼吸道感染的敏感性、特异性、阳性预测值、阴性预测值、准确率均高于CRP、WBC,差异具有统计学意义（P<0.05）。结论: 血清PCT检测对细菌性上呼吸道感染患儿的诊断效能较高,比CRP、WBC具有更高的诊断敏感性及特异性。

关键词: 细菌性上呼吸道感染, 降钙素原, 诊断