Abstract: Objective To systematically evaluate the related factors affecting the prognosis of stroke patients with dysphagia, so as to provide evidence for the rehabilitation guidance of clinical prognosis of stroke patients with dysphagia. Methods The related studies on the prognostic factors of dysphagia in stroke were searched in the databases of CNKI, WanFang, Cochrane Library, PubMed and Web of Science. The search time was limited from January 1, 2010 to May 1, 2020. Meta analysis was performed by software RevMan5.3. Results A total of 11 articles were included. The results of Meta analysis showed that age≥70 years old (OR=0.16, 95%CI), cognitive impairment (OR=0.11, 95%CI), sensory aphasia (OR=0.18, 95%CI), dysphagia degree (OR=0.11, 95%CI), rehabilitation intervention time (OR=-6.10). 95%CI (-6.54), brainstem damage (OR=0.14, 95%CI), BI<60 (OR=0.42, 95%CI) and NIHSS score≥12 (OR=0.20, 95%CI) were the factors affecting the prognosis of dysphagia in stroke. Conclusion The prognostic effect of stroke patients with dysphagia is affected by many factors. Targeted preventive intervention measures should be given to the controllable factors in order to speed up the rehabilitation process, lighten the burden and promote the patients to return to society as soon as possible.

Key words: stroke, dysphagia, influencing factors, meta analysis

摘要： 目的 系统评价影响脑卒中吞咽障碍患者预后的相关因素,以便为脑卒中吞咽障碍患者临床预后的康复指导提供证据支持。方法 检索CNKI、WanFang、Cochrane Library、PubMed、Web of Science数据库中有关影响脑卒中吞咽障碍预后因素的相关研究,检索时间限制为2010年1月1日~2020年5月1日,采用软件RevMan 5.3进行Meta分析。结果 最终纳入11篇文献,Meta分析结果显示,年龄≥70岁[OR=0.16,95％CI(0.05,0.46)]、认知障碍[OR=0.11,95％CI(0.08,0.15)]、感觉性失语[OR=0.18,95％CI(0.11,0.32)]、吞咽障碍程度[OR=0.11,95％CI(0.04,0.30)]、康复介入时间[OR=-6.10,95％CI(-6.54,-5.66)]、脑干受损[OR=0.14,95％CI(0.06,0.31)]、BI<60分[OR=0.42,95％CI(0.27,0.66)]、NIHSS评分≥12分[OR=0.20,95％CI(0.06,0.65)]是影响脑卒中吞咽障碍预后的因素。结论 脑卒中吞咽障碍患者的预后效果,受众多因素的影响,对于可控因素,给予针对性的预防干预措施,以期加快康复进程,减轻负担,促进患者尽早回归社会。

关键词: 脑卒中, 吞咽障碍, 影响因素, Meta分析