Abstract: Objective To investigate the application of 3D power doppler ultrasound (3D-PDU) and Shear wave elastography (SWE) on fetal growth restriction (FGR) placenta three-dimensional power doppler index and young's modulus value in quantitative analysis, and analyzes its diagnostic performance. Methods Thirty FGR pregnant women were selected as FGR group, and 45 healthy pregnant women were selected as control group. All pregnant women underwent three-dimensional power Doppler and shear wave elastography ultrasound examination from 25 to 36 weeks of gestation. Placental vascularization index (VI), flow index (FI), vascularization-flow index (VFI) and Young's modulus were collected. Results VI, FI, VFI in FGR group were significantly lower than those in control group (P<0.05). The Young's modulus of FGR group was higher than that of control group, and the difference was statistically significant (P<0.05). ROC curve shows the VI, FI and VFI in the area under the curve respectively 0.730, 0.673, 0.768. Conclusion Three-dimensional power doppler ultrasound parameters of joint shear wave elastography of FGR predictive value to a certain extent, and can be used for clinical screening of FGR.

Key words: Fetal growth restriction, Placenta, Three-dimensional power doppler, Shear wave elastography

摘要： 目的 应用三维能量多普勒超声技术（3D-PDU）和剪切波弹性成像（SWE）对胎儿生长受限（FGR）胎盘的3D-PDU指数和杨氏模量值进行定量分析,并分析其诊断效能。方法 选取FGR孕妇30例为FGR组,另选取同期产检健康孕妇45例为对照组。在孕25周到36周对所有孕妇进行3D-PDU和SWE超声检查,检测胎盘血管化指数(VI)、血流指数(FI)、血管化-血流指数(VFI)、杨氏模量值等指标。结果 FGR组的VI、FI、VFI以及均低于对照组,差异有统计学意义(P<0.05)。FGR组的杨氏模量值高于对照组,差异有统计学意义(P<0.05)。ROC曲线显示VI、FI、VFI曲线下面积分别为0.730、0.673、0.768。结论 3D-PDU参数联合SWE对FGR有一定的预测价值,可用于临床筛查FGR人群。

关键词: 胎儿生长受限, 胎盘, 三维能量多普勒, 剪切波弹性成像