ANAYLSIS OF THE RESULTS OF HPV INFECTION IN FEMALE GENITAL TRACT OF 13120 CASES IN CHENGDE

Journal of Chengde Medical University ›› 2019, Vol. 36 ›› Issue (2): 109-111.

ANAYLSIS OF THE RESULTS OF HPV INFECTION IN FEMALE GENITAL TRACT OF 13120 CASES IN CHENGDE

the Affiliated Hospital of Chengde Medical College, HeBei Chengde 067000, China

Received:2018-12-14 Online:2019-04-10 Published:2021-11-18

承德地区13120例女性生殖道HPV感染结果分析

王薇, 郭健, 陆海涛, 李雪飞, 刘利君, 段昕所^△

承德医学院附属医院,河北承德 067000

通讯作者: △

Abstract

Abstract: Objective: To analyze the genotype distribution and age distribution of human papillomavirus (HPV) infection of female in Hebei Chengde. Methods: Human papillomavirus nucleic acid typing detection kit was used to detect HPV infection of 13120 female in the Affiliated Hospital of Chengde Medical College, and the genotype distribution and age distribution of HPV infection were analyzed. Results: The HPV infection rate in 13120 female was 32.30% (4238/13120); 27 genotypes were detected, among which 16 genotype was the most, followed by 58, 52 and 6 genotype. In 4238 female, the constituent ratio of high-risk infection, low-risk infection and mixed infection were respectively 60.85%, 19.58% and 19.56%; the constituent ratio of single infection, double infection and multiple infection were respectivly 64.51%, 22.18% and 13.31%. The top three age groups of HPV infection rate were lower than 20 years old, 20-24 years old and 60-64 years old. Conclusions: The female HPV infection in Hebei Chengde area is mainly high-risk type and single infection, the genotypes with high infection rate were 16, 58, 52 and 6, and the distribution is U-shaped with age.

Key words: Chengde area, Human papillomavirus (HPV), Genotype, Age

摘要： 目的:分析河北省承德地区女性人乳头瘤病毒（HPV）感染的基因型别分布和年龄分布特征。方法:在承德医学院附属医院进行HPV感染检测的女性13120例,用人乳头瘤病毒核酸分型检测试剂盒检测HPV的基因型别,并分析年龄分布等特征。结果:13120例女性HPV感染率为32.30%（4238/13120）;27种基因亚型均有检出,以16型最多,其次为58型、52型、6型。4238例感染者中,高危型、低危型、混合感染构成比分别为60.85%、19.58%、19.56%,单一型、两重感染、多种感染的构成比分别为64.51%、22.18%、13.31%。年龄分布分析结果显示,感染率居前3位的年龄段是≤20岁、20~24岁,60~64岁。结论:河北省承德地区女性HPV感染主要以高危型、单一感染为主,感染率较高的基因型别是16型、58型、52型、6型,且随年龄呈U形分布。

关键词: 承德地区, 人乳头瘤病毒（HPV）, 基因分型, 年龄

CLC Number:

R711.3

WANG Wei, GUO Jian, LU Hai-tao, et al. ANAYLSIS OF THE RESULTS OF HPV INFECTION IN FEMALE GENITAL TRACT OF 13120 CASES IN CHENGDE[J]. Journal of Chengde Medical University, 2019, 36(2): 109-111.

王薇, 郭健, 陆海涛, 李雪飞, 刘利君, 段昕所. 承德地区13120例女性生殖道HPV感染结果分析[J]. 承德医学院学报, 2019, 36(2): 109-111.

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