Abstract: Objective To detect the relationship between obstructive sleep apnea hypopnea syndrome (OSAHS) and vestibular nerve function by cervical vestibular evoked myogenic potential (cVEMP). Methods Cervical vestibular evoked myogenic potential (cVEMP) of 54 OSAHS patients and 49 age-matched volunteers who matched the criteria was monitored to compare the indicators between the two groups. Results (1) The cVEMP extraction rate was lower in the OSAHS group than the normal group, and the differences of P1 latency, interwaveperiod, amplitude, and binaural asymmetry ratio (P<0.05) between tuo groups are statistically significant. The P1 latency and asymmetry ratio in the experimental group were larger than those in the control group, and the amplitude and interwave period were lower than those in the control group, while the N1 latency was not statistically significant (P>0.05). (2) The results of cVEMP in patients with mild, moderate OSAHS and severe OSAHS were not statistically significant. Conclusion Sleep apnea hypopnea syndrome can cause vestibular hypofunction.

Key words: sleep apnea hypopnea syndrome, vestibular evoked myogenic potential, inferior vestibular nerve

摘要： 目的 通过颈源性前庭诱发肌源性电位(cVEMP)来研究阻塞性睡眠呼吸暂停低通气综合征（OSAHS）与前庭神经功能的关系。方法 通过对54名OSAHS患者及年龄与之匹配的49名符合纳入标准的志愿者进行cVEMP的监测,对比两组间各个指标。结果 （1）OSAHS组患者与对照组的cVEMP引出率、P1潜伏期、波间期、振幅及双耳的不对称比差异有统计学意义（P<0.05）,实验组P1的潜伏期、不对称比均大于对照组,双耳的振幅及波间期小于对照组,N1的潜伏期差异无统计学意义(P>0.05)。（2）轻、中度及重度OSAHS患者的cVEMP各指标差异无统计学意义（P>0.05）。结论 阻塞性睡眠呼吸暂停低通气综合征可致前庭神经功能减退。

关键词: 阻塞性睡眠呼吸暂停低通气综合征, 前庭诱发肌源性电位, 前庭下神经