Objective To establish preparation methods of ursolic acid solid dispersions and evaluate the quality in vitro. Methods Ursolic acid solid dispersions (UA-SD) were obtained with different carriers by solvent method. Based on crystal suppression experiment, the carrier materials were screened out. The dissolution rate of UA-SD with different drug loading ratio was compared by dissolution test, and the optimal UA-SD drug loading ratio was screened then the solid dispersion was identified by scanning electron microscopy (SEM), differential scanning calorimetry (DSC), X-ray diffraction (X-RD) and fourier transform infrared spectroscopy (FT-IR). Results Soluplus was selected as the carrier of the preparation UA-SD by crystal suppression experiments. The dissolution in vitro showed that the cumulative dissolution rate of UA-SD at 120 minute was 102.7% with a mass ratio of drug to carrier of 1:11. Solid dispersion displayed a much higher dissolution rate than raw medicine and physical mixture. The SEM, DSC, XRD and FT-IR characterizations showed that UA exist in solid dispersions in amorphous form. Conclusion Preparation of UA-SD with Soluplus as carrier can significantly increase the dissolution rate of ursolic acid.