Objective To investigate the lipid-lowering effects and protective effects on liver of Lifeceramics (LC) on rats with hyperlipidemia. Methods SD rats were randomly divided into 5 groups with 12 rats in each group: blank control group, model group, LC low-dose group, LC high-dose group and atorvastatin group. The hyperlipidemia rats model was establised by long-term high-fat and high-sugar diet; At the same time, the rats in the treatment group were lavaged with LC of different dose and atorvastatin for 20 weeks respectively. The total cholesterol (TC), triglyceride (TG) and low density lipoprotein cholesterin (LDL-C) of rats in each group were detected respectively; the liver index of rats was calculated; the gross morphology of liver was observed; HE stain was used to observe the organization structure of liver. Results Compared with rats in model group, the TC, TG, LDL-C and liver index of rats in LC low-dose group and LC high-dose group reduced significantly (P<0.05, P<0.01). There were no significant differences about TC, TG, LDL-C and liver index between LC low-dose group and LC high-dose group (P>0.05). The gross morphology observation showed that the liver lesions in LC treatment group were significantly reduced compared with model group. HE staining displayed that the steatosis of hepatocytes in LC treatment group lightened significantly compared with model group. Conclusion LC can obviously reduces the blood lipid and has obviously protective effects on liver of hyperlipidemia rats; LC has obvious protective effects on liver injury induced by long-term high-fat and high-sugar diet.