Objective To detect the relationship between obstructive sleep apnea hypopnea syndrome (OSAHS) and vestibular nerve function by cervical vestibular evoked myogenic potential (cVEMP). Methods Cervical vestibular evoked myogenic potential (cVEMP) of 54 OSAHS patients and 49 age-matched volunteers who matched the criteria was monitored to compare the indicators between the two groups. Results (1) The cVEMP extraction rate was lower in the OSAHS group than the normal group, and the differences of P1 latency, interwaveperiod, amplitude, and binaural asymmetry ratio (P<0.05) between tuo groups are statistically significant. The P1 latency and asymmetry ratio in the experimental group were larger than those in the control group, and the amplitude and interwave period were lower than those in the control group, while the N1 latency was not statistically significant (P>0.05). (2) The results of cVEMP in patients with mild, moderate OSAHS and severe OSAHS were not statistically significant. Conclusion Sleep apnea hypopnea syndrome can cause vestibular hypofunction.

Objective: To analyze the clinical effects for treating high frequency descending sudden deafness with batroxobin combine methylprednisolone sodium succinate. Methods: 80 cases of high frequency descending sudden deafness patients were randomly divided into experimental group and control group with 40 patients in each group. The patients in experimental group were treated with vinpocetine+methylprednisolone sodium succinate+ batroxobin, the patients in control group were treated with vinpocetine+methylprednisolone sodium succinate. The curative effects and incidence of adverse reactions of patients in 2 groups were observed after 2 weeks' treatment. Results: The total effective rate of experimental group was 87.5% (35/40), which was obviously higher than control group (60.0%, 24/40, P<0.05). There was no significant difference in the incidence rate of adverse reactions between the two groups, such as dizziness, diarrhoea and facial blushing (P>0.05). Conclusions: Treating high frequency descending sudden deafness with batroxobin combine methylprednisolone sodium succinate can improve the therapeutic effect, and without increasing adverse reactions.