Objective To explore the safety test and clinical efficacy evaluation of 3D printing image contrast technology model in Sanders type II (sanders II) calcaneal fractures. Methods Retrospective analysis of 46 cases of sandersII calcaneal fracture treated in Affiliated Hospital of Chengde Medical University from May 2014 to October 2021 was made. According to the preoperative plan, patients were divided into mirror image technique group (23 cases) and radiology technique group (23 cases), the measured data of scaphoid bone and fifth metatarsal bone of the affected side and the healthy side were compared by mirror image. The clinical effects were evaluated by preoperative, perioperative and follow-up indexes. Results The measured data of scaphoid bone and fifth metatarsal bone of the affected side and the contralateral side were compared in the mirror image technique group,there was no significant difference between the two groups (P>0.05), so it was safe to use the mirror image technique in preoperative planning. There were significant differences in pre-operative planning related cost, pre-operative planning related time and fracture reduction time between the two groups (P>0.05). All patients were followed up for 9-15 months with an average of (12.48±2.26) months. There was a significant difference in fracture healing rate between the two groups (P>0.05), and there was no significant difference in Maryland foot function between the two groups (P>0.05). Conclusion The application of 3D printing mirror image contrast technique in sandersII type calcaneal fracture is safe and reliable, and the clinical effect is definite, but it will increase the economic and time burden of patients.