Objective To analyze the current research status, hotspots and trends of hawthorn leaves at home and abroad through CiteSpace knowledge mapping and bibliometrics, and provide references for its comprehensive utilization and subsequent research. Methods The Chinese and English literatures on the topic of hawthorn leaves were exported from the core collections of CNKI and Web of Science databases. After screening, 822 Chinese and 213 English literatures were included. CiteSpace was used to visualize the analysis of information such as Chinese and English authors, publishing institutions, and keywords. Results There were 44 core authors of Chinese hawthorn leaves and 97 core authors of English hawthorn leaves. Pan Haifeng was the author with the highest number of Chinese and English articles published. The main publishing institutions were universities and research institutes. The co-occurrence and clustering analysis of keywords showed that the research hotspots of hawthorn leaves mainly focused on total flavonoids, etc., and the research directions were concentrated on chemical components, etc. Keyword emergence suggested that hyperlipidemia, oxidative stress, inflammation and antioxidant are the future development direction. Conclusion The research popularity of hawthorn leaf at home and abroad shows an increasing trend of fluctuation, but inter-provincial institutional cooperation is insufficient, and it is necessary to strengthen communication and further improve the new detection methods, accurate quality control, and basic research on pharmacodynamic substances.

Objective To establish an HPLC method for measuring the content of Chaihu saponina, c and d, which is used to compare the differences in the content of wild beichaihu in different origin cultivation areas of Beichaihu and Chengde City, Hebei Province. Methods The content of Chaihu saponin a, c and d in 27 batches of different samples of Beichaihu was determined by high-efficiency liquid chromatography, and the correlationship was analysed. Results The quality of cultivated chaihu was significantly higher than that of wild Chaihu, the highest level of Chaihu saponin a was in Beichahu, Gansu Kang County, and the highest content of Chaihu saponin d was in Beichaihu of Gansu Province, most of which were not detected by the wild beihu saponin c, and the cultivation of beihu saponin c was detected. The color and saponin content of Chaihugen were significantly correlated, the yellow root saponin a, d content was the highest, the black root content was second, and the root color had little effect on the content of Chaihu saponin c. Conclusion The content of artificial cultivation of Beichaihu saponina, c and d is higher than that of wild Chaihu, and it is found that the content of beichaihugen color and saponin content are significantly correlated, which provides theoretical basis for the establishment and evaluation of Chaihu resource utilization and quality analysis methods of medicinal herbs.